Toxicology 2
|
Steffen
Loft
Professor, Institute of Public Health, University of Copenhagen |
The toxicology sessions will cover the latest scientific research into the biological impact of engineered nanoparticles on the human body and the environment, in order to disseminate findings and to create cooperation and exchange in this field of research.
Contents
Cytotoxicity of inorganic nanoparticles on human cells
|
Manuel
Arruebo
Research Associate, Department of Chemical and Environmental Engineering and Aragon Nanoscience Institute, University of Zaragoza, Spain |
Nanotoxico: Toxicological assessment of engineered nanoparticles using in vitro and in vivo models
|
Stéphanie
Rolin
PhD in Pharmaceutical Sciences, Dpt. of Pharmacy - University of Namur |
Nanosciences and nanotechnologies are highly promising areas for research and industrial innovation. Due to their remarkable properties, nanomaterials are bearing many hopes, notably in materials engineering, in environmental sector and in medicine. Whilst this technology has enormous potential benefit, there are concerns that nanomaterials may generate a new class of risk on health and environment not only for workers chronically exposed to nanoparticles, but also for population in general indirectly exposed.
Risk assessment of engineered nanoparticles: the Particle Risk project
|
Giulio
Pojana
, Department of Environmental Sciences, University Ca’ Foscari of Venice |
Engineered nanoparticles are being increasingly used in various commercial products and for specific applications, resulting in a serious concern for the potential exposure to humans and the environment. Currently, very little is known about the potential risk to human health and environment of nanomaterials.
Effects of a panel of nanoparticles on mutagenicity, DNA damage, ROS levels and the cell cycle in the Muta™mouse lung epithelial
|
Nicklas Raun
Jacobsen
, National Research Centre for the Working Environment |
Carbon black (CB), diesel exhaust particles (DEP), quartz, single-walled carbon nanotubes (SWCNT) and C60 fullerenes (C60) were investigated for cytotoxicity, genotoxicity, ROS production, proliferation effects and mutagenicity in the FE1-Muta™Mouse lung cell line. Mutagenicity was studied using a parallel continuous sub-culture setup. Cells were incubated for 72 h with either pure media or a test substances (100 ug/ml quartz, SWCNT or C60)(75 ug/ml of CB or DEP)(37.5 ug/ml DEP) through eight subsequent exposure rounds.